Collect Data
Diary Entries. Surveys. Wellness Checks.
Send Reminders
Custom Schedules. Personalised Profiles. Conditional Triggers.
Manage Data
Diary Entries. Personal Profiles. Escalations. General Data Collection
Previous slide
Next slide

How to Improve Study Compliance and Medication Adherence using mComply

Understand how trial coordinators and research organisations can improve study  compliance through effective participant engagement. In our updated brochure “mComply: Running Successful Clinical Trials – Compliance Delivered” we share how our mComply solution can improve medication adherence and overall study compliance. A workflow of how to achieve study compliance is shared on our partner website. Alternatively, watch our video describing our realtime patient diary and dose reminder tool for clinical trials.

Why is Study Compliance and Medication Adherence Important?​

With adherence rates in clinical trials ranging from 39% – 63% for prevention trials and 59% – 78% for treatment trials, compliance tools are instrumental to realising successful trials. Interventions to improve medication adherence showed increases in adherence in the range of 4% – 11%.1,2,3  The financial impact is enormous. Improving nonadherence by 1% in a typical Phase 2 trial could result in nearly $400,000 in cost savings and reduces the time to market.4

Improve Study Compliance with mComply

Compliance can be improved through effective participant engagement. Using Synegys’ mComply, high adherence rates can be achieved by sending participants timely messages including appointment, medication and diary entry reminders and motivation messages. Moreover, diary entry submissions and other forms of data collection can be automated with the use of mobile phones. mComply offers a tailored approach based on optimal timing, adaptation and content. With customizable logic applications and conditional triggers, mComply fully supports organisations to collect data and to improve overall study compliance. The solution supports any customer-facing interface including any one or combination of text messaging, mobile app, email, interactive voice response, web portal or live agents. Given the ubiquitous reach of text messaging, this platform is the most popular. SMS / text-based programs are the most simple, straightforward, and effective for getting information to people and allowing them to interact quickly.

97% of mobile users read text messages in 15 minutes5

Find out how mComply can help your Organization

Request our updated brochure mComply: Running Successful Clinical Trials – Compliance Delivered from our health division mobileHealthWorks to understand the productivity improvements and cost / revenue benefits this solution can bring to your organization.


1 Robiner, William N. Enhancing adherence in clinical trials. Contemporary Clinical Trials. 2005;26:59–77.

2 Andrew M. Peterson, Liza Takiya, Rebecca Finley. Meta-Analysis of Trials of Interventions to Im- prove Medication Adherence. Am J Health Syst Pharm. 2003;60(7).

3 Alsumidaie Moe, Non-Adherence: A Direct Influence on Clinical Trial Duration and Cost, Applied Clinical Trials, Apr 2017.

4 Synegys Analysis

5 Smart Insights – “Benefits of SMS Marketing”. May 12, 2020.